BDBM700146 US20240335569, Compound 3BP-3951

SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCNC(=O)C(=C\Nc2ccc3nccc(C(=O)NCC(=O)N4CCC[C@H]4C#N)c3c2)\N=N)CCN(CC(O)=O)CC1

InChI Key InChIKey=KHILKYSUPYWYCM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 700146   

TargetDipeptidyl peptidase 4(Human)
3 B Pharmaceuticals

US Patent
LigandPNGBDBM700146(US20240335569, Compound 3BP-3951)
Affinity DataIC50: 1.00E+3nMAssay Description:PREP activity was measured with recombinant human PREP (R&D systems, #4308-SE). The PREP activity assay was performed using the FACS buffer (PBS incl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
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TargetPresequence protease, mitochondrial(Human)
3 B Pharmaceuticals

US Patent
LigandPNGBDBM700146(US20240335569, Compound 3BP-3951)
Affinity DataIC50: 1.00E+3nMAssay Description:PREP activity was measured with recombinant human PREP (R&D systems, #4308-SE). The PREP activity assay was performed using the FACS buffer (PBS incl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
3 B Pharmaceuticals

US Patent
LigandPNGBDBM700146(US20240335569, Compound 3BP-3951)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent