BDBM699814 US20240335427, Compound 44

SMILES O=C(Nc1ncc(s1)-c1ccc(cc1)C(=O)NCC#C)[C@H]1CCN(C1)C#N

InChI Key InChIKey=DTRLNFTTYGKPEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699814   

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699814(US20240335427, Compound 44)
Affinity DataIC50: 8.25E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
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Date in BDB:
2/10/2025
Entry Details
Go to US Patent