BDBM699305 Synthesis of N-((3S, 15S, 18aS, 19aR, 19bS, Z)-3-cyano-19,19-dimethyl-1,6,16-trioxo-1,3,4,5,6,7,8,9,10,13,14,15,16,18,18a,19,19a,19b-octadec ahydro-2H-cyclopropane[3,4]pyrrole[1,2-a][1,4,9]triazacyclooctadecene-15-yl)-2,2,2-trifluoroaceta mide ::US20240327458, Compound 4

SMILES CC1(C)[C@H]2CN3[C@@H]([C@@H]12)C(=O)N[C@@H](CCC(=O)NCCC\C=C/CC[C@H](NC(=O)C(F)(F)F)C3=O)C#N

InChI Key InChIKey=HDQHKUCAKLFVIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699305   

TargetReplicase polyprotein 1a(SARS-CoV)
Tencent Technology (Shenzhen)

US Patent
LigandPNGBDBM699305(Synthesis of N-((3S, 15S, 18aS, 19aR, 19bS, Z)-3-c...)
Affinity DataIC50: 411nMAssay Description:An objective of this experiment is to detect the in vitro inhibitory activity against Mpro of the compound of the present disclosure.Experimental mat...More data for this Ligand-Target Pair
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Date in BDB:
2/3/2025
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