BDBM699272 2'-chloro-N-{5-[(1,1-dioxo-1-6-thietan- 3-yl)methoxy]-1,3-benzothiazol-2-yl}- 5'-methoxy-6-methyl-[4,4'-bipyridine]- 3-carboxamide::US12145945, Example 113::US20240327430, Example 113

SMILES COc1cnc(Cl)cc1-c1cc(C)ncc1C(=O)Nc1nc2cc(OCC3CS(=O)(=O)C3)ccc2s1

InChI Key InChIKey=SASUZKMDDIITQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 699272   

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM699272(2'-chloro-N-{5-[(1,1-dioxo-1-6-thietan- 3-yl)metho...)
Affinity DataIC50: 550nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Pol&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM699272(2'-chloro-N-{5-[(1,1-dioxo-1-6-thietan- 3-yl)metho...)
Affinity DataIC50: 550nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Polθ protein (P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
Go to US Patent