BDBM699186 US20240327430, Example 27

SMILES COc1cnc(Cl)cc1-c1cc(C)ncc1C(=O)Nc1nc2cnc(nc2s1)N1CCS(=O)(=O)CC1

InChI Key InChIKey=XNFOWYPAKHDNIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699186   

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM699186(US20240327430, Example 27)
Affinity DataIC50: 1.00E+3nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Pol&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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