BDBM699151 US20240327425, Compound I-17-2

SMILES CC(Oc1nc2N3C[C@H]4CC[C@H](N4)[C@@H]3COc3c(Cl)c(c(F)c(n1)c23)-c1cccc2sc(N)c(C#N)c12)[C@@]12CCCN1C[C@@H](F)C2

InChI Key InChIKey=BDKLAVHFZVYACN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 699151   

TargetGTPase KRas [G12D](Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM699151(US20240327425, Compound I-17-2)
Affinity DataIC50: 6.90nMAssay Description:The binding ability of the compound to KRAS G12D protein was detected by TR-FRET method, and the inhibitory activity of the compound on KRAS G12D pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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