BDBM699122 US20240327418, Example LEE21

SMILES CCCNNC(=O)c1ccc(CNC(=O)c2cc3ccncc3[nH]2)cc1

InChI Key InChIKey=VCLVJEOEQLBTEN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 699122   

TargetHistone deacetylase 1(Human)
Ocean University of China

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 8.17nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Ocean University of China

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 51.5nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Ocean University of China

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 2.42nMAssay Description:a) Formulation of 100% solution: 50 μL of HDAC buffer was mixed with 10 μL of enzyme solution, 40 μL of substrate was added after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Ocean University of China

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

US Patent
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM699122(US20240327418, Example LEE21)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed