BDBM698901 Tritiated (R)-2-(2-fluoro-6-(3-fluoropyrrolidin-1-yl)pyridin-3-yl)-5-(pyridin-4-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one 3H-Compound 7::US20260103474, Example 10

SMILES Nc1cc(N2CCc3nc(-c4ccc(N5CCCC5)nc4F)sc3C2=O)ccc1F

InChI Key InChIKey=DYZIJHIGTBIXOB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698901   

TargetTAR DNA-binding protein 43(Human)
AC Immune

US Patent
LigandChemical structure of BindingDB Monomer ID 698901BDBM698901(Tritiated (R)-2-(2-fluoro-6-(3-fluoropyrrolidin-1-...)
Affinity DataKi:  350nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent