BDBM698898 5-(1-((1-(((4-((R)-3-hydroxy-3-methylpiperidin- 1-yl)-6-(3-hydroxy-8-iodo-1-naphthoyl)-6,7- dihydro-5H-pyrrolo[3,4-d]pyrimidin-2- yl)oxy)methyl)cyclopropyl)methyl)piperidin-3- yl)-1,3,4-oxadiazol-2(3H)-one::US20240317759, Example 107

SMILES O=C1c2sc(-c3ccc(N4CC[C@@H](F)C4)nc3F)nc2CCN1c1ccncc1

InChI Key InChIKey=SXVUVDUMDQYHHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698898   

TargetTAR DNA-binding protein 43(Human)
AC Immune

US Patent
LigandChemical structure of BindingDB Monomer ID 698898BDBM698898(ethyl 1-(6-fluoro-5-(4-oxo-5-(pyridin-3-yl)-4,5,6,...)
Affinity DataKi: >1.00E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2026
Entry Details
US Patent