BDBM698086 US20240317714, Example A78

SMILES CN1CCC(CC1)n1cc(Oc2nc(cnc2N)-c2cc(cc(c2)C2(O)COC2)N2CC3(COC3)C2)cn1

InChI Key InChIKey=BQWPRYZZSGQBAQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698086   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Beigene

US Patent

LigandBDBM698086(US20240317714, Example A78)Copy SMILESCopy InChI

Affinity DataIC50: 5.5nMAssay Description:Compounds disclosed herein were tested for inhibition of HPK1 kinase (aal-346. Life Technologies) activity in assays based on the time-resolved fluor...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/28/2025
Entry Details
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