BDBM698084 US20240317714, Example A76

SMILES COC[C@@H]1COCCN1c1cc(cc(c1)C1(O)COC1)-c1cnc(N)c(Oc2cnn(c2)C2CCN(C)CC2)n1

InChI Key InChIKey=FBCJJPAXTQQXNM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698084   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Beigene

US Patent

LigandBDBM698084(US20240317714, Example A76)Copy SMILESCopy InChI

Affinity DataIC50: 5.80nMAssay Description:Compounds disclosed herein were tested for inhibition of HPK1 kinase (aal-346. Life Technologies) activity in assays based on the time-resolved fluor...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/28/2025
Entry Details
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