BDBM698068 US20240317714, Example A61B

SMILES CN1CCC(CC1)n1cc(Oc2nc(cnc2N)-c2cc(C)cc(c2)[C@H]2CCC(=O)N2)cn1

InChI Key InChIKey=IDZRBXGIFWUYTI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 698068   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Beigene

US Patent

LigandBDBM698068(US20240317714, Example A61B)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Compounds disclosed herein were tested for inhibition of HPK1 kinase (aal-346. Life Technologies) activity in assays based on the time-resolved fluor...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/28/2025
Entry Details
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