BDBM697575 US20240316047, Example 356

SMILES Cc1sc(cc1-c1ccc(cn1)C(F)(F)F)C(=O)Nc1cc(Cl)cc(NS(C)(=O)=O)c1

InChI Key InChIKey=KXTOZGRWLAVUNL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 697575   

TargetATP-dependent RNA helicase A(Human)
Accent Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 697575BDBM697575(US20240316047, Example 356)
Affinity DataEC50:  45nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetATP-dependent RNA helicase A(Human)
Accent Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 697575BDBM697575(US20240316047, Example 356)
Affinity DataEC50:  130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetATP-dependent RNA helicase A(Human)
Accent Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 697575BDBM697575(US20240316047, Example 356)
Affinity DataIC50: 148nMAssay Description:Recombinant DHX9-Human recombinant DHX9 protein was custom ordered from Viva.RNA substrateĀ—Oligos for double-stranded RNA substrate were custom order...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
US Patent