BDBM697211 1-[[2- (difluoromethoxy) pyridin-4- yl]methyl]-3- [rac-(2R,3S)-3- hydroxyspiro[3.3] heptan-2-yl]urea::US20240316020, Example 26

SMILES O[C@H]1[C@H](CC11CCC1)NC(=O)NCc1ccnc(OC(F)F)c1

InChI Key InChIKey=PKKATWMGZDLLPZ-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 697211   

TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
Icagen

US Patent

LigandBDBM697211(US20240316020, Example 26 | 1-[[2- (difluoromethox...)Copy SMILESCopy InChI

Affinity DataEC50:  440nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/28/2025
Entry Details
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