BDBM697209 1-[[2- (difluoromethoxy) pyridin-4- yl]methyl]-3- (2,2- difluorospiro[2.3] hexan-1-yl)urea::US20240316020, Example 24

SMILES FC(F)Oc1cc(CNC(=O)NC2C(F)(F)C22CCC2)ccn1

InChI Key InChIKey=LRTSEIJKOXSAKN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 697209   

LigandPNGBDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  340nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697209(US20240316020, Example 24 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent