BDBM697208 1-[[2- (difluoromethoxy) pyridin-4- yl]methyl]-3- spiro[2.3]hexan- 2-ylurea::US20240316020, Example 23

SMILES FC(F)Oc1cc(CNC(=O)NC2CC22CCC2)ccn1

InChI Key InChIKey=IZELMLRSZYLEIO-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 697208   

LigandPNGBDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  1.94E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50:  1.94E+3nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

LigandPNGBDBM697208(US20240316020, Example 23 | 1-[[2- (difluoromethox...)
Affinity DataEC50: >3.00E+4nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent