BDBM697198 1-[2-hydroxy-1- [2-(2,2,2- trifluoroethoxy) pyridin-4- yl]ethyl]-3- spiro[3.3]heptan- 2-ylurea::US20240316020, Example 13

SMILES OCC(NC(=O)NC1CC2(CCC2)C1)c1ccnc(OCC(F)(F)F)c1

InChI Key InChIKey=LWVWGWMRFXMDSZ-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 697198   

TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
Icagen

US Patent

LigandBDBM697198(US20240316020, Example 13 | 1-[2-hydroxy-1- [2-(2,...)Copy SMILESCopy InChI

Affinity DataEC50:  70nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/28/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL