BDBM697197 1- spiro[2.3]hexan- 5-yl-3-[[2-(2,2,2- trifluoroethoxy) pyridin-4- yl]methyl]urea::US20240316020, Example 12

SMILES FC(F)(F)COc1cc(CNC(=O)NC2CC3(CC3)C2)ccn1

InChI Key InChIKey=FPAZCQVFKBQWDF-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 697197   

TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
Icagen

US Patent

LigandBDBM697197(US20240316020, Example 12 | 1- spiro[2.3]hexan- 5-...)Copy SMILESCopy InChI

Affinity DataEC50:  170nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/28/2025
Entry Details
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