BDBM697189 1-[[2- (difluoromethoxy) pyridin-4- yl]methyl]-3- spiro[3.3]heptan- 2-ylurea::US20240316020, Example 4

SMILES FC(F)Oc1cc(CNC(=O)NC2CC3(CCC3)C2)ccn1

InChI Key InChIKey=KGEPLZDZFRKYFR-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 697189   

TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
Icagen

US Patent

LigandBDBM697189(US20240316020, Example 4 | 1-[[2- (difluoromethoxy...)Copy SMILESCopy InChI

Affinity DataEC50:  20nMAssay Description:Human Kv7.2, Kv7.4 or Kv7.5/7.3 channels were evaluated using a voltage protocol in which cells were voltage-clamped at a holding potential of -60 mV...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/28/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL