BDBM696370 1-[(5-bromo-6-{6,6-difluoro-3-aza-::US12091399, Example 51

SMILES FC1(F)C2CN(CC12)c1ncc(Cn2cc(cn2)C(=O)NCc2cc(Cl)ccc2-n2cnnn2)cc1Br

InChI Key InChIKey=DKMPKYGRNIOHJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696370   

TargetPlasma kallikrein(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM696370(1-[(5-bromo-6-{6,6-difluoro-3-aza- | US12091399, E...)
Affinity DataIC50: 2nMAssay Description:Human PKK (0.01 U/mL; Enzyme Research Laboratories) or rat PKK (0.625 nM; produced in-house) was incubated for 1 h at rt with 0.10 μM fluorogeni...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
1/13/2025
Entry Details
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