BDBM696343 N-{[5-chloro-2-(1H-1,2,3,4-tetrazol-1-::US12091399, Example 24

SMILES Cc1nc(ncc1Cn1cc(C(=O)NCc2cc(Cl)ccc2-n2cnnn2)c2cncnc12)N1CC2C(C1)C2(F)F

InChI Key InChIKey=XZXCUWCPSGOLBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696343   

TargetPlasma kallikrein(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM696343(N-{[5-chloro-2-(1H-1,2,3,4-tetrazol-1- | US1209139...)
Affinity DataIC50: 2nMAssay Description:Human PKK (0.01 U/mL; Enzyme Research Laboratories) or rat PKK (0.625 nM; produced in-house) was incubated for 1 h at rt with 0.10 μM fluorogeni...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/13/2025
Entry Details
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