BDBM696336 N-{[3-chloro-2-fluoro-6-(1H-1,2,3,4-::US12091399, Example 17

SMILES Cc1nn(Cc2ccc(nc2C)N2CC3C(C2)C3(F)F)cc1C(=O)NCc1c(F)c(Cl)ccc1-n1cnnn1

InChI Key InChIKey=BHSNSJBIIQQTSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696336   

TargetPlasma kallikrein(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM696336(N-{[3-chloro-2-fluoro-6-(1H-1,2,3,4- | US12091399,...)
Affinity DataIC50: 0.400nMAssay Description:Human PKK (0.01 U/mL; Enzyme Research Laboratories) or rat PKK (0.625 nM; produced in-house) was incubated for 1 h at rt with 0.10 μM fluorogeni...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
1/13/2025
Entry Details
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