BDBM696211 US20240300937, Example 117

SMILES CC(C)c1c(cnc2c(F)cc(cc12)-c1nc(Cl)ncc1Cl)C(C)(C)O

InChI Key InChIKey=KIKLVQCDRAYAMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 696211   

LigandPNGBDBM696211(US20240300937, Example 117)
Affinity DataIC50: 2.10nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
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LigandPNGBDBM696211(US20240300937, Example 117)
Affinity DataIC50: 54nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent