BDBM696207 US20240300937, Example 68

SMILES CC(C)c1c(CN2[C@@H](C)COC[C@H]2C)cnc2ccc(cc12)-c1nc(N[C@@H]2CCOC[C@H]2O)ncc1F

InChI Key InChIKey=ZNAVDFQDONRFBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 696207   

LigandPNGBDBM696207(US20240300937, Example 68)
Affinity DataIC50: 8.70nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent

LigandPNGBDBM696207(US20240300937, Example 68)
Affinity DataIC50: 395nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent