BDBM696203 US20240300937, Example 60

SMILES CC(C)c1c(CN2C3CCCC2CC(O)C3)cnc2ccc(cc12)-c1nc(N[C@@H]2CCOC[C@H]2O)ncc1F

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 696203   

LigandPNGBDBM696203(US20240300937, Example 60)
Affinity DataIC50: 15nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent

LigandPNGBDBM696203(US20240300937, Example 60)
Affinity DataIC50: 585nMAssay Description:Compounds disclosed herein were tested for inhibition of CDK4/Cyclin D1 or CDK6/Cyclin D3 kinase in an assay based on the time-resolved fluorescence-...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent