BDBM696122 US20240300936, Example 118

SMILES Cc1ncc2ccc(cn12)-c1nc(N)nc(NC2(CCCC2)c2ccn(n2)C(F)F)n1

InChI Key InChIKey=HWJLRACGLDFOHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 696122   

TargetSerine/threonine-protein kinase greatwall(Human)
Avelos Therapeutics

US Patent
LigandPNGBDBM696122(US20240300936, Example 118)
Affinity DataIC50: 2.24nMAssay Description:Wild-type human MASTL (0.5 nM) was incubated in assay buffer (30 mM HEPES, 100 mM NaCl, 0.5 mM EGTA, 10 mM MgCl2, 0.01% Tween-20, 0.5 mM TCEP, pH 7.5...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent