BDBM696001 6-cyclopropyl-N-(3-(3-((R)-fluoro(4- methyl-4H-1,2,4-triazol-3- yl)methyl)oxetan-3-yl)phenyl)-4-(((S)-2- isopropyl-4-methylpiperazin-1- yl)methyl)picolinamide::US20240300927, Compound 499

SMILES CC(C)[C@H]1CN(C)CCN1Cc1cc(nc(c1)C(=O)Nc1cccc(c1)C1(COC1)[C@@H](F)c1nncn1C)C1CC1

InChI Key InChIKey=ADWBUODILRPWSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 696001   

LigandPNGBDBM696001(US20240300927, Compound 499 | 6-cyclopropyl-N-(3-(...)
Affinity DataIC50: 11nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent

LigandPNGBDBM696001(US20240300927, Compound 499 | 6-cyclopropyl-N-(3-(...)
Affinity DataIC50: 7nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent