BDBM696000 (S)-6-cyclopropyl-4-((2-isopropyl-4- methylpiperazin-1-yl)methyl)-N-(3-(3- ((4-methyl-4H-1,2,4-triazol-3- yl)methyl)oxetan-3- yl)phenyl)picolinamide::US20240300927, Compound 498

SMILES CC(C)[C@H]1CN(C)CCN1Cc1cc(nc(c1)C(=O)Nc1cccc(c1)C1(Cc2nncn2C)COC1)C1CC1

InChI Key InChIKey=OECKUNKMKVTWCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 696000   

LigandPNGBDBM696000(US20240300927, Compound 498 | (S)-6-cyclopropyl-4-...)
Affinity DataIC50: 10nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent

LigandPNGBDBM696000(US20240300927, Compound 498 | (S)-6-cyclopropyl-4-...)
Affinity DataIC50: 6.20nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent