BDBM695995 (S)-6-cyclopropyl-N-(3-(3,3-difluoro-1- ((4-methyl-4H-1,2,4-triazol-3- yl)methyl)cyclobutyl)phenyl)-4-((2- isopropyl-4-methylpiperazin-1- yl)methyl)picolinamide::US20240300927, Compound 224

SMILES CC(C)[C@H]1CN(C)CCN1Cc1cc(nc(c1)C(=O)Nc1cccc(c1)C1(Cc2nncn2C)CC(F)(F)C1)C1CC1

InChI Key InChIKey=XMQIODWUIJUJJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695995   

LigandPNGBDBM695995(US20240300927, Compound 224 | (S)-6-cyclopropyl-N-...)
Affinity DataIC50: 7.5nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent

LigandPNGBDBM695995(US20240300927, Compound 224 | (S)-6-cyclopropyl-N-...)
Affinity DataIC50: 5nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent