BDBM695950 2-((1r,4r)-4-(2-(1-hydroxyethyl)-1H-imidazol-1-yl)cyclohexyl)-6-methoxy-N-(1-methyl-2-oxo-1,2-dihydropyridin-3-yl)-2H-indazole-5-carboxamide::US20240300923, Example 28

SMILES COc1cc2nn(cc2cc1C(=O)Nc1cccn(C)c1=O)[C@H]1CC[C@@H](CC1)n1ccnc1[C@H](C)O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695950   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

US Patent
LigandPNGBDBM695950(US20240300923, Example 28 | 2-((1r,4r)-4-(2-(1-hyd...)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of compounds against IRAK4 were determined in an enzymatic assay using mass spectrometry readout. Ten point half-log compound...More data for this Ligand-Target Pair
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Date in BDB:
1/8/2025
Entry Details
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TargetMast/stem cell growth factor receptor Kit(Human)
Astrazeneca

US Patent
LigandPNGBDBM695950(US20240300923, Example 28 | 2-((1r,4r)-4-(2-(1-hyd...)
Affinity DataIC50: 1.06E+4nMAssay Description:Potency of IRAK4 Inhibitor Compounds in cKit Enzyme Assay. Evaluation of the effects of the IRAK4 inhibitor compounds on the activity of the human cK...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent