BDBM695944 (R)-4-(5-azaspiro[2.4]heptan-5- ylmethyl)-6-cyclopropyl-N-(3-(3- (fluoro(4-methyl-4H-1,2,4-triazol-3- yl)methyl)oxetan-3- yl)phenyl)picolinamide::US20240300927, Compound 5

SMILES Cn1cnnc1[C@H](F)C1(COC1)c1cccc(NC(=O)c2cc(CN3CCC4(CC4)C3)cc(n2)C2CC2)c1

InChI Key InChIKey=VRIUQJQJYNDQLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695944   

LigandPNGBDBM695944(US20240300927, Compound 5 | (R)-4-(5-azaspiro[2.4]...)
Affinity DataIC50: 19nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent

LigandPNGBDBM695944(US20240300927, Compound 5 | (R)-4-(5-azaspiro[2.4]...)
Affinity DataIC50: 30nMAssay Description:Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 concentrat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent