BDBM695918 US20240299360, Example 33

SMILES CC[C@H](C[C@]1(NC(=O)NC1=O)C1CC1)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F

InChI Key InChIKey=GYAIYJXOPICREB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695918   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM695918(US20240299360, Example 33)
Affinity DataIC50: 18nMAssay Description:Table 2: In this assay, the enzymatic activity of recombinant ADAMTS-5 protein (catalog #2198-AD, R&D Systems) was assayed with a protein substrate, ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent