BDBM695800 6-(3-{[3-(4-fluorophenyl)butyl]carbamoyl}-4- methylpiperazin-1-yl)-N-methyl-1H-indazole-3- carboxamide::US12084426, Example 19

SMILES CNC(=O)c1n[nH]c2cc(ccc12)N1CCN(C)C(C1)C(=O)NCCC(C)c1ccc(F)cc1

InChI Key InChIKey=OXZZJPZVLYLUKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695800   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM695800(US12084426, Example 19 | 6-(3-{[3-(4-fluorophenyl)...)
Affinity DataIC50: 790nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent