BDBM695794 6-(3-{[3-(4- fluorophenoxy)propyl]carbamoyl}piperidin-1- yl)-N-methyl-1H-indazole-3-carboxamide::US12084426, Example 13

SMILES CNC(=O)c1n[nH]c2cc(ccc12)N1CCCC(C1)C(=O)NCCCOc1ccc(F)cc1

InChI Key InChIKey=HRXBSOWBPJOTPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 695794   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM695794(US12084426, Example 13 | 6-(3-{[3-(4- fluorophenox...)
Affinity DataIC50: 1.30E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent