BDBM695510 US12083118, Example 30::US20240374595, Example 30

SMILES COc1cc(OCc2cccc(c2C)-c2cccc(COc3cc(OC)c(CN4CCCC[C@H]4C(O)=O)cc3Cl)c2C)c(Cl)cc1CO

InChI Key InChIKey=XBBDWHIUGOJDNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695510   

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM695510(US12083118, Example 30 | US20240374595, Example 30)
Affinity DataIC50: 4nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM695510(US12083118, Example 30 | US20240374595, Example 30)
Affinity DataIC50: 4nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent