BDBM695502 US12083118, Example 22::US20240374595, Example 22

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(cc2Cl)C2=NCCN2CCO)cccc1-c1cccc(OCCCN2CCC(O)CC2)c1C

InChI Key InChIKey=UJHMRULCJSYKTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695502   

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM695502(US12083118, Example 22 | US20240374595, Example 22)
Affinity DataIC50: 3.80nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM695502(US12083118, Example 22 | US20240374595, Example 22)
Affinity DataIC50: 3.80nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent