BDBM6954 3,11-diazatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-1,3,5,7,9,12,14,16-octaene::carbazole deriv. 14

SMILES c1ccc2c(c1)[nH]c1ccc3cccnc3c21

InChI Key InChIKey=MZXDPTWGJXNUMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6954   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Dupont Pharmaceuticals

LigandPNGBDBM6954(3,11-diazatetracyclo[8.7.0.0^{2,7}.0^{12,17}]hepta...)
Affinity DataIC50: 4.42E+5nMpH: 7.6 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 mM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2005
Entry Details Article
PubMed