BDBM694238 6-(3,3-difluorocyclobutoxy)-7-(difluoromethyl)- 2,2,3,3-tetrafluoro-2,3-dihydro-1H-inden-1-ol::US12077506, Compound I-8

SMILES OC1c2c(ccc(OC3CC(F)(F)C3)c2C(F)F)C(F)(F)C1(F)F

InChI Key InChIKey=FUIRGMJMDYLWPM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694238   

TargetVascular endothelial growth factor A(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM694238(6-(3,3-difluorocyclobutoxy)-7-(difluoromethyl)- 2,...)
Affinity DataEC50:  105nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2alpha was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
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