BDBM694234 7-(difluoromethyl)-6-(3,5-difluorophenoxy)-2,2,3,3- tetrafluoro-2,3-dihydro-1H-inden-1-ol::US12077506, Compound I-4

SMILES OC1c2c(ccc(Oc3cc(F)cc(F)c3)c2C(F)F)C(F)(F)C1(F)F

InChI Key InChIKey=HNHYIOAAPNHGHQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694234   

TargetVascular endothelial growth factor A(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM694234(7-(difluoromethyl)-6-(3,5-difluorophenoxy)-2,2,3,3...)
Affinity DataEC50:  4nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2alpha was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
Go to US Patent