BDBM694223 3-((4-(difluoromethyl)-1,1,2,2-tetrafluoro-3-hydroxy- 2,3-dihydro-1H-inden-5-yl)oxy)-5-fluorobenzonitrile::US12077506, Compound I-1

SMILES OC1c2c(ccc(Oc3cc(F)cc(c3)C#N)c2C(F)F)C(F)(F)C1(F)F

InChI Key InChIKey=XHPOCDMHJOXJBT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 694223   

TargetVascular endothelial growth factor A(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM694223(US12077506, Compound I-1 | 3-((4-(difluoromethyl)-...)
Affinity DataEC50:  6nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2alpha was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
12/16/2024
Entry Details
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