BDBM693932 US20240287079, Example 101

SMILES Cc1cc(C)c(c(C)c1)-n1cc2c(n1)nc([nH]c2=O)N1CCN(CC1)C(=O)OC(C)(C)C

InChI Key InChIKey=AWUXNYOZPJYWEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693932   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM693932(US20240287079, Example 101)
Affinity DataIC50: 5.60nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated on the basis of the inhibitory activity of the IL-1β production in T...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent