BDBM693647 US20240287022, Example 98

SMILES O=c1[nH]c2ccccc2cc1Cc1ccc(cc1)C1(CC1)C#N

InChI Key InChIKey=XFVHNJPKOMEDQT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 693647   

TargetL-amino-acid oxidase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM693647(US20240287022, Example 98)
Affinity DataEC50:  1nMAssay Description:Inhibition of recombinant IL4I1 (unknown origin) assessed as reduction in H2O2 production preincubated for 4 hrs followed by Phe/Tyr/Trp addition mea...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetL-amino-acid oxidase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM693647(US20240287022, Example 98)
Affinity DataEC50:  1nMAssay Description:nterleukin 4 inducible protein 1 (IL4I1) is an L-amino oxidase that catalyzes the oxidation of aromatic residues (Phe, Trp and Tyr): L-amino acid+H2O...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent