BDBM693491 N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N- methylethan-1-amine::US20240286998, Compound 12::US20240317683, Compound 4

SMILES CCN(C)CCc1c[nH]c2ccc(F)cc12

InChI Key InChIKey=XRWQULAXCLVBPP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 693491   

TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM693491(N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N- methylethan-...)
Affinity DataIC50: 419nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Saint Joseph'S University

US Patent
LigandPNGBDBM693491(N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N- methylethan-...)
Affinity DataKi:  219nMAssay Description:ValiScreen Serotonin 5-HT2A (human) cell line (product No: ES-313-C) grown in DMEM/F12 media augmented with 10% FBS, 4 mM GlutaMAX, 0.4 mg/mL Genetic...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent