BDBM693467 1-(3-methoxyphenyl)-N-(2,3,6-trifluoro- 4-((3-(2-(((3S,5S)-5-fluoropiperidin-3- yl)amino)pyrimidin-4-yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide::US12071425, Compound 385

SMILES COc1cccc(CS(=O)(=O)Nc2c(F)cc(Oc3ncccc3-c3ccnc(N[C@@H]4CNC[C@@H](F)C4)n3)c(F)c2F)c1

InChI Key InChIKey=CIXXYBIJLLQBFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693467   

LigandPNGBDBM693467(1-(3-methoxyphenyl)-N-(2,3,6-trifluoro- 4-((3-(2-(...)
Affinity DataIC50: 0.200nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
12/6/2024
Entry Details
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