BDBM693461 1-(4-cyanophenyl)-N-(2,3-difluoro-4-((3- (2-(((S)-piperidin-3-yl)amino)pyrimidin- 4-yl)pyridin-2-yl)oxy)phenyl)ethane-1- sulfonamide::US12071425, Compound 379

SMILES CC(c1ccc(cc1)C#N)S(=O)(=O)Nc1ccc(Oc2ncccc2-c2ccnc(N[C@H]3CCCNC3)n2)c(F)c1F

InChI Key InChIKey=LEUBNNTXQLLRSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693461   

LigandPNGBDBM693461(1-(4-cyanophenyl)-N-(2,3-difluoro-4-((3- (2-(((S)-...)
Affinity DataIC50: 0.300nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
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Date in BDB:
12/6/2024
Entry Details
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