BDBM693443 3-fluoro-4-[[2,3,6-trifluoro-4-[[3-[2- [[(3S,5S)-5-fluoro-3- piperidyl]amino]pyrimidin-4-yl]-2- pyridyl]oxy]phenyl]sulfamoyl- methyl]benzamide::US12071425, Compound 361

SMILES NC(=O)c1ccc(CS(=O)(=O)Nc2c(F)cc(Oc3ncccc3-c3ccnc(N[C@@H]4CNC[C@@H](F)C4)n3)c(F)c2F)c(F)c1

InChI Key InChIKey=KWBQKCUCKFJPPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693443   

LigandPNGBDBM693443(3-fluoro-4-[[2,3,6-trifluoro-4-[[3-[2- [[(3S,5S)-5...)
Affinity DataIC50: 0.300nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/6/2024
Entry Details
Go to US Patent