BDBM693397 1-(4-cyclopropylphenyl)-N-(2,3,6- trifluoro-4-((3-(2-(((3S,5S)-5- fluoropiperidin-3-yl)amino)pyrimidin-4- yl)pyridin-2- yl)oxy)phenyl)methanesulfonamide::US12071425, Compound 315

SMILES F[C@@H]1CNC[C@H](C1)Nc1nccc(n1)-c1cccnc1Oc1cc(F)c(NS(=O)(=O)Cc2ccc(cc2)C2CC2)c(F)c1F

InChI Key InChIKey=VPTZKZWPAKZBHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693397   

LigandPNGBDBM693397(1-(4-cyclopropylphenyl)-N-(2,3,6- trifluoro-4-((3-...)
Affinity DataIC50: 0.230nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
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Date in BDB:
12/6/2024
Entry Details
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