BDBM693393 N-(2,5-difluoro-4-((3-(2-(((3S,5S)-5- fluoro-5-methylpiperidin-3- yl)amino)pyrimidin-4-yl)pyridin-2- yl)oxy)-3-methylphenyl)-1-(p- tolyl)methanesulfonamide::US12071425, Compound 311

SMILES Cc1ccc(CS(=O)(=O)Nc2cc(F)c(Oc3ncccc3-c3ccnc(N[C@@H]4CNC[C@@](C)(F)C4)n3)c(C)c2F)cc1

InChI Key InChIKey=NTURJVJGNXDCGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693393   

LigandPNGBDBM693393(N-(2,5-difluoro-4-((3-(2-(((3S,5S)-5- fluoro-5-met...)
Affinity DataIC50: 0.290nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
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Date in BDB:
12/6/2024
Entry Details
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