BDBM693392 N-(4-((3-(2-(((1r,4r)-4- (dimethylamino)cyclohexyl)amino)pyrimi- din-4-yl)pyridin-2-yl)oxy)-2,3,6- trifluorophenyl)-3,3-difluorobutane-1- sulfonamide::US12071425, Compound 310

SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1nccc(n1)-c1cccnc1Oc1cc(F)c(NS(=O)(=O)CCC(C)(F)F)c(F)c1F

InChI Key InChIKey=RGXXXJUXLRRSCC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693392   

LigandPNGBDBM693392(N-(4-((3-(2-(((1r,4r)-4- (dimethylamino)cyclohexyl...)
Affinity DataIC50: 0.320nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
12/6/2024
Entry Details
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