BDBM693362 N-(2,3-difluoro-4-((3-(2-(((3S,5S)-5- fluoro-5-methylpiperidin-3- yl)amino)pyrimidin-4-yl)pyridin-2- yl)oxy)-6-methylphenyl)-1- phenylmethanesulfonamide::US12071425, Compound 279

SMILES Cc1cc(Oc2ncccc2-c2ccnc(NC3CNC[C@@](C)(F)C3)n2)c(F)c(F)c1NS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=GLYFQVPDOLFKQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 693362   

LigandPNGBDBM693362(N-(2,3-difluoro-4-((3-(2-(((3S,5S)-5- fluoro-5-met...)
Affinity DataIC50: 0.230nMAssay Description:To determine the affinity of compound binding to the kinase domain of IRE1 alpha, a Time Resolved Fluorescence Resonance Energy Transfer (TR-FRET) co...More data for this Ligand-Target Pair
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Date in BDB:
12/6/2024
Entry Details
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